Possible infection requesting registry change for TMIS - detected by Spybot Search and Destroy

I helped a friend with a badly infected laptop yesterday (effectively now needs a complete reinstall of Win XP) and may have picked up an infection in my machine.

I think this may have happened when I scanned and cleaned two USB sticks with important data. Both had infections. From scribbled notes, we found Trj_Link.tj, PE.Virut and worm.cheburgen.b. 

My machine is a Dell Studio 1737 running Vista Professional.  I run a fully updated version of Trend Micro Internet Security with Spybot Search and Destory in the background.  My concern relates to Spybot Search and Destroy notifying me this morning of an automatically blocked registry change relating to Trend Micro Internet Security/tsc.exe /HD

I've scanned with TMIS and am currently running a freshly downloaded freeware version of Avast just to be sure(r).

I also ran HijackThis:

Logfile of Trend Micro HijackThis v2.0.4 Scan saved at 6:56:32 AM, on 7/11/2010 Platform: Windows Vista SP2 (WinNT 6.00.1906) MSIE: Internet Explorer v8.00 (8.00.6001.18975) Boot mode: Normal Running processes: C:\Windows\system32\taskeng.exe C:\Windows\system32\Dwm.exe C:\Windows\Explorer.EXE C:\Program Files\IObit\Advanced SystemCare 3\AWC.exe C:\Program Files\IDT\WDM\sttray.exe C:\Program Files\DellTPad\Apoint.exe C:\Program Files\Trend Micro\Internet Security\UfSeAgnt.exe C:\Program Files\Vodafone\Vodafone Mobile Connect\Bin\MobileConnect.exe C:\Program Files\Microsoft Office\Office12\GrooveMonitor.exe C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe C:\Program Files\Common Files\Nokia\MPlatform\NokiaMServer.exe C:\Program Files\Common Files\Java\Java Update\jusched.exe C:\Program Files\CyberLink\InstantBurn\Win2K\IBurn.exe C:\Program Files\CyberLink\Power2Go\CLMLSvc.exe C:\Program Files\DellTPad\ApMsgFwd.exe C:\Program Files\DellTPad\Apntex.exe C:\Program Files\DellTPad\HidFind.exe C:\Program Files\DigitalPersona\Bin\DpAgent.exe C:\Program Files\Sierra Wireless Inc\WebUpdater\TRUUpdater.exe C:\Program Files\Telstra\Telstra Connection Manager\WaHelper.exe C:\Program Files\Common Files\Ahead\Lib\NMBgMonitor.exe C:\Program Files\Skype\Phone\Skype.exe C:\ProgramData\Macrovision\FLEXnet Connect\6\ISUSPM.exe C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe C:\Program Files\Windows Media Player\wmpnscfg.exe C:\Program Files\WIDCOMM\Bluetooth Software\BTTray.exe C:\Program Files\Dell\QuickSet\quickset.exe C:\Program Files\Common Files\Ahead\Lib\NMIndexStoreSvr.exe C:\Windows\system32\wbem\unsecapp.exe C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe C:\Program Files\WIDCOMM\Bluetooth Software\BtStackServer.exe C:\Program Files\Vodafone\Vodafone Mobile Connect\Optimization Client\bmctl.exe C:\Program Files\Skype\Plugin Manager\skypePM.exe C:\Program Files\Opera\opera.exe C:\Program Files\Trend Micro\HiJackThis\HiJackThis.exe C:\Windows\system32\SearchFilterHost.exe R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896 R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://au.tv.yahoo.com/tv-guide R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157 R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896 R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896 R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157 R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName = O1 - Hosts: ::1 localhost O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll O2 - BHO: DigitalPersona Fingerprint Software Extension - {395610AE-C624-4f58-B89E-23733EA00F9A} - C:\Program Files\DigitalPersona\Bin\DpOtsPluginIe8.dll O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\Program Files\Microsoft Office\Office12\GrooveShellExtensions.dll O2 - BHO: SkypeIEPluginBHO - {AE805869-2E5C-4ED4-8F7B-F1F7851A4497} - C:\Program Files\Skype\Toolbars\Internet Explorer\skypeieplugin.dll O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files\Java\jre6\bin\jp2ssv.dll O4 - HKLM\..\Run: [Windows Defender] %ProgramFiles%\Windows Defender\MSASCui.exe -hide O4 - HKLM\..\Run: [SysTrayApp] C:\Program Files\IDT\WDM\sttray.exe O4 - HKLM\..\Run: [Apoint] C:\Program Files\DellTPad\Apoint.exe O4 - HKLM\..\Run: [NeroFilterCheck] C:\Program Files\Common Files\Ahead\Lib\NeroCheck.exe O4 - HKLM\..\Run: [UfSeAgnt.exe] "C:\Program Files\Trend Micro\Internet Security\UfSeAgnt.exe" O4 - HKLM\..\Run: [MobileConnect] C:\Program Files\Vodafone\Vodafone Mobile Connect\Bin\MobileConnect.exe /silent O4 - HKLM\..\Run: [GrooveMonitor] "C:\Program Files\Microsoft Office\Office12\GrooveMonitor.exe" O4 - HKLM\..\Run: [Google Desktop Search] "C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe" /startup O4 - HKLM\..\Run: [NokiaMServer] C:\Program Files\Common Files\Nokia\MPlatform\NokiaMServer /watchfiles startup O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Common Files\Java\Java Update\jusched.exe" O4 - HKLM\..\Run: [InstantBurn] C:\PROGRA~1\CYBERL~1\INSTAN~1\Win2K\IBurn.exe O4 - HKLM\..\Run: [CLMLServer] "C:\Program Files\CyberLink\Power2Go\CLMLSvc.exe" O4 - HKLM\..\Run: [UpdateP2GoShortCut] "C:\Program Files\CyberLink\Power2Go\MUITransfer\MUIStartMenu.exe" "C:\Program Files\CyberLink\Power2Go" UpdateWithCreateOnce "SOFTWARE\CyberLink\Power2Go\6.0" O4 - HKLM\..\Run: [DpAgent] C:\Program Files\DigitalPersona\Bin\dpagent.exe O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 9.0\Reader\Reader_sl.exe" O4 - HKLM\..\Run: [Adobe ARM] "C:\Program Files\Common Files\Adobe\ARM\1.0\AdobeARM.exe" O4 - HKLM\..\Run: [TRUUpdater] "C:\Program Files\Sierra Wireless Inc\WebUpdater\TRUUpdater.exe" /bkground O4 - HKLM\..\Run: [WatcherHelper] "C:\Program files\Telstra\Telstra Connection Manager\WaHelper.exe" O4 - HKCU\..\Run: [BgMonitor_{79662E04-7C6C-4d9f-84C7-88D8A56B10AA}] "C:\Program Files\Common Files\Ahead\Lib\NMBgMonitor.exe" O4 - HKCU\..\Run: [Skype] "C:\Program Files\Skype\Phone\Skype.exe" /nosplash /minimized O4 - HKCU\..\Run: [ISUSPM] "C:\ProgramData\Macrovision\FLEXnet Connect\6\ISUSPM.exe" -scheduler O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE') O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE') O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE') O4 - Global Startup: Bluetooth.lnk = ? O4 - Global Startup: QuickSet.lnk = C:\Program Files\Dell\QuickSet\quickset.exe O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office12\EXCEL.EXE/3000 O8 - Extra context menu item: Send image to &Bluetooth Device... - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm O8 - Extra context menu item: Send page to &Bluetooth Device... - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~2\Office12\ONBttnIE.dll O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~2\Office12\ONBttnIE.dll O9 - Extra button: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files\Skype\Toolbars\Internet Explorer\skypeieplugin.dll O9 - Extra 'Tools' menuitem: Skype add-on for Internet Explorer - {898EA8C8-E7FF-479B-8935-AEC46303B9E5} - C:\Program Files\Skype\Toolbars\Internet Explorer\skypeieplugin.dll O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\Office12\REFIEBAR.DLL O9 - Extra button: @btrez.dll,-4015 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm O9 - Extra 'Tools' menuitem: @btrez.dll,-12650 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll O10 - Unknown file in Winsock LSP: bmnet.dll O10 - Unknown file in Winsock LSP: bmnet.dll O10 - Unknown file in Winsock LSP: bmnet.dll O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\Program Files\Microsoft Office\Office12\GrooveSystemServices.dll O18 - Protocol: skype-ie-addon-data - {91774881-D725-4E58-B298-07617B9B86A8} - C:\Program Files\Skype\Toolbars\Internet Explorer\skypeieplugin.dll O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~1\COMMON~1\Skype\SKYPE4~1.DLL O20 - AppInit_DLLs: C:\PROGRA~1\Google\GOOGLE~1\GOEC62~1.DLL O22 - SharedTaskScheduler: Component Categories cache daemon - {8C7461EF-2B13-11d2-BE35-3078302C2030} - C:\Windows\system32\browseui.dll O23 - Service: Andrea ST Filters Service (AESTFilters) - Andrea Electronics Corporation - C:\Windows\System32\DriverStore\FileRepository\stwrt.inf_559ad4ac\aestsrv.exe O23 - Service: AMD External Events Utility - AMD - C:\Windows\system32\atiesrxx.exe O23 - Service: AuthenTec Fingerprint Service (ATService) - AuthenTec, Inc. - C:\Program Files\Fingerprint Sensor\AtService.exe O23 - Service: Bluetooth Service (btwdins) - Broadcom Corporation. - C:\Program Files\WIDCOMM\Bluetooth Software\bin\btwdins.exe O23 - Service: @C:\Program Files\DigitalPersona\Bin\DpHostW.exe,-128 (DpHost) - DigitalPersona, Inc. - C:\Program Files\DigitalPersona\Bin\DpHostW.exe O23 - Service: Google Desktop Manager 5.9.1005.12335 (GoogleDesktopManager-051210-111108) - Google - C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe O23 - Service: NBService - Nero AG - C:\Program Files\Nero\Nero 7\Nero BackItUp\NBService.exe O23 - Service: NMIndexingService - Nero AG - C:\Program Files\Common Files\Ahead\Lib\NMIndexingService.exe O23 - Service: SBSD Security Center Service (SBSDWSCService) - Safer Networking Ltd. - C:\Program Files\Spybot - Search & Destroy\SDWinSec.exe O23 - Service: ServiceLayer - Nokia - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe O23 - Service: Trend Micro Central Control Component (SfCtlCom) - Trend Micro Inc. - C:\Program Files\Trend Micro\Internet Security\SfCtlCom.exe O23 - Service: Audio Service (STacSV) - IDT, Inc. - C:\Windows\System32\DriverStore\FileRepository\stwrt.inf_559ad4ac\STacSV.exe O23 - Service: Trend Micro Unauthorized Change Prevention Service (TMBMServer) - Trend Micro Inc. - C:\Program Files\Trend Micro\BM\TMBMSRV.exe O23 - Service: Trend Micro Proxy Service (TmProxy) - Trend Micro Inc. - C:\Program Files\Trend Micro\Internet Security\TmProxy.exe O23 - Service: Vodafone Mobile Connect Service (VMCService) - Vodafone - C:\Program Files\Vodafone\Vodafone Mobile Connect\Bin\VMCService.exe -- End of file - 10949 bytes

Am I being paranoid about the Spybot S&D detection or do I have a problem here?

Can I permit the requested registry change relating to Trend Micro Internet Security/TSC.exe /HD?

Is there anything else I need to do to ensure my machine is both clean and protected?

Cliffo