You can run virtual nodes on an ESXi server by deploying the OVA file on a selected ESXi host.
https://<your-vcenter-dnsname or ip_address_of_vcenter>:9443/vsphere-client/
isi license add —evaluation ONEFS,SMARTQUOTAS,SNAPSHOTIQ,SMARTCONNECT_ADVANCED,SYNCIQ,SMARTPOOLS,SMARTLOCK,HDFS,SMARTDEDUPE,CLOUDPOOLS,SWIFT,HARDENING